Skip to main content


Springer Nature is making Coronavirus research free. View research | View latest news | Sign up for updates

Figure 2 | Journal of Biology

Figure 2

From: Molecular machines or pleiomorphic ensembles: signaling complexes revisited

Figure 2

Averaging leads to loss of information. In the panel on the right, each pixel is the average of the properties of all the individual pixels in the panel on the left. By averaging, all information on the range of properties of individual pixels, and their spatial distribution, is lost. Most biochemical methods used to probe signaling complexes, such as immunoprecipitation followed by immunoblotting or mass spectrometry, average the properties of complexes over the entire population.

Back to article page