Distribution of GO terms for genes or proteins involved in genetic and physical interactions compared with genome-wide distribution. (a) Distribution of indicated GO cellular component, molecular function and biological process terms for nodes in each dataset. Sce refers to the distribution for all genes or proteins. (b) Fraction of interactions that share common GO terms in each of the three GO categories. High-level GO annotations (GO-Slim) were obtained from the SGD. The mean shared annotation is significantly higher for LC-PI than for HTP-PI for each of the three categories (Fisher's exact test, P < 1 × 10-10).