The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans

Table 2 Axon outgrowth and guidance defects of HSN, DD/VD, ALA and AVK neurons

Axon guidance phenotype	Defect in unc-69(e587) mutants (%)	n
HSN
Ventral outgrowth	16	70
Midline crossover (HSNL)	38	40
Failure to reach nerve ring	99	59
DD/VD
Dorsal outgrowth	33	45
ALA
Premature termination	67	30
AVKR
Premature termination or crossover	85	20

The morphology of HSN neurons was visualized using antibodies against serotonin; that of DD/VD neurons using antibodies against GABA; and that of ALA and AVKR neurons using antibodies against FMRF-amide. See Materials and methods for details. n, number of animals scored.