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Table 2 Amino-acid biosynthetic enzymes with protein levels consistently up- and downregulated with growth rate under all nutrient-limiting conditions

From: Growth control of the eukaryote cell: a systems biology study in yeast

  Enzymes
Amino-acid biosynthetic pathway Upregulated Downregulated
Arginine Aco1p, Aco2p, Cpa1p, Cpa2p Arg1p, Arg8p
Homocysteine, cysteine, methionine, and sulfur compounds Ecm17p, Met10p, Met13p, Sam2p, Met6p, Ado1p Sam1p
Glutamine Gln1p  
Leucine, isoleucine, valine Ilv3p, Leu1p  
Lysine Aco1p, Aco2p, Lys2p, Lys4p  
  1. Aco1p, aconitase; Aco2p, putative aconitase isozyme; Ado1p; adenosine kinase; Arg1p, arginosuccinate synthetase; Arg8p, acetylornithine aminotransferase; Cpa1p, small subunit of carbamoyl phosphate synthetase; Cpa2p, large subunit of carbamoyl phosphate synthetase; Ecm17p, sulfite reductase beta subunit; Gln1p, glutamine synthetase; Ilv3p, dihydroxyacid dehydratase; Leu1p, isopropylmalate isomerase; Lys2p, alpha aminoadipate reductase; Lys4p, homoaconitase; Met6p, methionine synthase; Met10p, sulfite reductase alpha subunit; Met13p, methylenetetrahydrofolate reductase isozyme; Sam1p, S-adenosylmethionine synthetase isozyme; Sam2p, S-adenosylmethionine synthetase isozyme.