| Copper | Cadmium | Fluoranthene | Atrazine | TNT |
---|---|---|---|---|---|
Species | L. rubellus | L. rubellus | L. rubellus | L. rubellus | Eisenia fetida |
Exposure time | 70 days | 28 days | 28 days | 28 days | 28 days |
Exposure concentration range (mg/kg) | 10-480 | 13-500 | 14-533 | 19-59 | 2-39 |
Metabolic category | Â | Â | Â | Â | Â |
   Detoxification | Y | Y | Y | Y |  |
   Oxidative stress | Y | Y | Y |  | Y |
   Mitochondrial electron transport | Y | Y | Y | Y | Y |
   Calcium binding and signaling | Y | Y |  |  | Y |
   Iron homeostasis and oxygen transport | Y | Y |  |  | Y |
   Blood coagulation and fibrinolysis |  |  |  |  | Y |
   Impaired immune function |  | Y |  |  | Y |
   Protein damage repair and catabolism | Y |  | Y | Y |  |
   Lipid metabolism | Y |  |  |  |  |
   Glycolysis and carbohydrate metabolism | Y |  |  |  |  |
   Cell cycle and apoptosis | Y |  |  | Y |  |
   Muscle contraction |  | Y |  |  | Y |
   DNA damage and repair |  | Y |  | Y |  |
   Neurological dysfunction |  |  |  |  | Y |
References | [10] | [11] | [11] | [11] |