Table 1 Useful links to therapy, disease, drug and drug-target network data
From: Drug-therapy networks and the prediction of novel drug targets
Name | Description | References |
|---|---|---|
DrugBank | A bioinformatics-cheminformatics resource combining detailed drug data with comprehensive drug target information with over 4,900 drug entries (about 3,500 experimental) and about 1,500 non-redundant protein entries | [26] |
Drug-target Network | Network data of 890 drugs and 394 target human proteins | [6] |
Drug-Therapy Network | Three layers of drug-therapy networks according to the ATC classification | [8] |
Online Mendelian Inheritance in Man (OMIM) | A knowledgebase of human genes and genetic disorders | [27] |
Potential Drug Target Database (PDTD) | A three-dimensional drug target structure database with a target identification option | [28] |
Predicted drug targets | A set of 1,383 predicted drug targets | [17] |
Protein ligand network | A network of 4,208 ligands and about 15,000 binding sites | [9] |
Therapeutic Target Database | Lists over 1,500 therapeutic targets, disease conditions and corresponding drugs | [29] |
FDA Orange Book | Approved drug products with therapeutic equivalence evaluations | [32] |
Investigational Drugs database (IDdb) | Thomson Investigational drugs database including information on 107,000 patents, 25,000 investigational drugs and 80,000 chemical structures | [33] |
TDR Targets Database | Identification and ranking targets against neglected tropical diseases | [34] |