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  1. Content type: Research article

    For genes that have been successfully delineated within the human genome sequence, most regulatory sequences remain to be elucidated. The annotation and interpretation process requires additional data resource...

    Authors: Boris Lenhard, Albin Sandelin, Luis Mendoza, Pär Engström, Niclas Jareborg and Wyeth W Wasserman

    Citation: Journal of Biology 2003 2:13

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  2. Content type: Editorial

    The momentum towards open-access publishing has continued to build in the months since Journal of Biology was launched.

    Authors: Theodora Bloom

    Citation: Journal of Biology 2003 2:1

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  3. Content type: Research news

    Mammalian cells, unlike yeast, seem to maintain a constant distribution of cell sizes without a cell-size checkpoint.

    Authors: Jonathan B Weitzman

    Citation: Journal of Biology 2003 2:3

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  4. Content type: Research news

    Technical wizardry has made possible the combination of two powerful methodologies, optical trapping and single-molecule fluorescence, to measure precisely the force required to unzip DNA.

    Authors: Jonathan B Weitzman

    Citation: Journal of Biology 2003 2:2

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  5. Content type: Research article

    Two of the mainstay techniques in single-molecule research are optical trapping and single-molecule fluorescence. Previous attempts to combine these techniques in a single experiment – and on a single macromol...

    Authors: Matthew J Lang, Polly M Fordyce and Steven M Block

    Citation: Journal of Biology 2003 2:6

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  6. Content type: Editorial

    Several aspects of Journal of Biology seem to have caught readers' attention. Some of the questions asked have arisen sufficiently often to be worth addressing here.

    Authors: Martin Raff, Theodora Bloom and Peter Newmark

    Citation: Journal of Biology 2002 1:6

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  7. Content type: Research article

    The Hedgehog (Hh) signaling pathway is vital to animal development as it mediates the differentiation of multiple cell types during embryogenesis. In adults, Hh signaling can be activated to facilitate tissue ...

    Authors: Maria Frank-Kamenetsky, Xiaoyan M Zhang, Steve Bottega, Oivin Guicherit, Hynek Wichterle, Henryk Dudek, David Bumcrot, Frank Y Wang, Simon Jones, Janine Shulok, Lee L Rubin and Jeffery A Porter

    Citation: Journal of Biology 2002 1:10

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  8. Content type: Research news

    An approach using 'chemical genetics' has identified small-molecule agonists of the Hedgehog signaling pathway that may lead the way to drugs for chronic degenerative diseases.

    Authors: Jonathan B Weitzman

    Citation: Journal of Biology 2002 1:7

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  9. Content type: Minireview

    The finding that neighboring eukaryotic genes are often expressed in similar patterns suggests the involvement of chromatin domains in the control of genes within a genomic neighborhood.

    Authors: Brian Oliver, Michael Parisi and David Clark

    Citation: Journal of Biology 2002 1:4

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  10. Content type: Research news

    An analysis of numerous Drosophila microarray experiments reveals that the genome has many large groups of adjacent genes that are expressed similarly but are not functionally related.

    Authors: Jonathan B Weitzman

    Citation: Journal of Biology 2002 1:2

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  11. Content type: Comment

    None of the advantages of traditional scientific journals need be sacrificed in order to provide free online access to scientific journal articles. Objections that open access to scientific journal literature ...

    Authors: Peter Suber

    Citation: Journal of Biology 2002 1:3

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  12. Content type: Editorial

    In launching a new journal that aspires to join the 'top rank' of biological publications, we have chosen an approach that differs from that of traditional journals in a number of ways.

    Authors: Martin Raff, Theodora Bloom and Peter Newmark

    Citation: Journal of Biology 2002 1:1

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