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Table 2 RNAi screen results classified by annotated phenotype

From: A functional genomic analysis of cell morphology using RNA interference

  

Genes identified*

Phenotypic class†

Total

Total S2R+

Total Kc167

Both‡

Cell shape

105

93

32

20

F-actin organization

94

74

50

30

Microtubule organization

71

48

37

14

Decreased cell density

66

62

8

4

Cell size

48

25

33

10

DNA morphology

27

17

22

12

Cell viability

6

3

4

1

Total phenotypes

417

322 (77%)

186 (44%)

91 (22%)

Total genes

160

146 (91%)

79 (49%)

65 (41%)

  1. *The number of genes categorized with a specific RNAi phenotype in duplicate screens. †The major classes of RNAi phenotypes. Individual genes with multiple phenotypes were counted within each of the phenotypic classes scored. ‡Genes identified by a defect assigned to the same phenotypic class in both cell types.
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Journal of Biology

ISSN: 1475-4924