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  1. Content type: Minireview

    Because emotions enhance memory processes and music evokes strong emotions, music could be involved in forming memories, either about pieces of music or about episodes and information associated with particula...

    Authors: Lutz Jäncke

    Citation: Journal of Biology 2008 7:21

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  2. Content type: Minireview

    A recent study in BMC Pharmacology presents a network of drugs and the therapies in which they are used. Network approaches open new ways of predicting novel drug targets and overcoming the cellular robustness th...

    Authors: Zoltan Spiro, Istvan A Kovacs and Peter Csermely

    Citation: Journal of Biology 2008 7:20

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  3. Content type: Minireview

    Transcription and metabolite analysis is a powerful way to reveal physiological shifts in response to environmental pollution. Recent studies on earthworms, including one in BMC Biology, show that the type of pol...

    Authors: Nico M van Straalen and Dick Roelofs

    Citation: Journal of Biology 2008 7:19

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  4. Content type: Research article

    Cancer treatment with a variety of chemotherapeutic agents often is associated with delayed adverse neurological consequences. Despite their clinical importance, almost nothing is known about the basis for suc...

    Authors: Ruolan Han, Yin M Yang, Joerg Dietrich, Anne Luebke, Margot Mayer-Pröschel and Mark Noble

    Citation: Journal of Biology 2008 7:12

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  5. Content type: Minireview

    Chemotherapy adversely affects cognitive function both acutely and chronically, but little is known about the underlying mechanisms. A new study shows that short-term chemotherapy causes not only acute injury ...

    Authors: Christina A Meyers

    Citation: Journal of Biology 2008 7:11

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  6. Content type: Research article

    Insulin and insulin-like growth factors (IGFs) signal through a highly conserved pathway and control growth and metabolism in both vertebrates and invertebrates. In mammals, insulin-like growth factor binding ...

    Authors: Basil Honegger, Milos Galic, Katja Köhler, Franz Wittwer, Walter Brogiolo, Ernst Hafen and Hugo Stocker

    Citation: Journal of Biology 2008 7:10

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  7. Content type: Minireview

    Breast cancers differ in many ways, such as in their cell of origin, the molecular alterations causing them and the susceptibility and defenses of the patient, and this makes it difficult to give the most appr...

    Authors: François Bertucci and Daniel Birnbaum

    Citation: Journal of Biology 2008 7:6

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  8. Content type: Minireview

    Long interspersed nuclear elements (LINEs) are among the most successful parasitic genetic sequences in higher organisms. Recent work has discovered many instances of LINE incorporation into exons, reminding u...

    Authors: Kathleen H Burns and Jef D Boeke

    Citation: Journal of Biology 2008 7:5

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  9. Content type: Research article

    The dissection of biological pathways and of the molecular basis of disease requires devices to analyze simultaneously a staggering number of protein isoforms in a given cell under given conditions. Such devic...

    Authors: David Evans, Steven Johnson, Sophie Laurenson, A Giles Davies, Paul Ko Ferrigno and Christoph Wälti

    Citation: Journal of Biology 2008 7:3

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  10. Content type: Minireview

    Peptide aptamers are combinatorial recognition proteins that were introduced more than ten years ago. They have since found many applications in fundamental and therapeutic research, including their recent use...

    Authors: Pierre Colas

    Citation: Journal of Biology 2008 7:2

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  11. Content type: Research article

    Eukaryotic cells have evolved various response mechanisms to counteract the deleterious consequences of oxidative stress. Among these processes, metabolic alterations seem to play an important role.

    Authors: Markus Ralser, Mirjam M Wamelink, Axel Kowald, Birgit Gerisch, Gino Heeren, Eduard A Struys, Edda Klipp, Cornelis Jakobs, Michael Breitenbach, Hans Lehrach and Sylvia Krobitsch

    Citation: Journal of Biology 2007 6:10

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  12. Content type: Minireview

    DNA studies are revealing the extent of hidden, or cryptic, biodiversity. Two new studies challenge paradigms about cryptic biodiversity and highlight the importance of adding a historical and biogeographic di...

    Authors: Luciano B Beheregaray and Adalgisa Caccone

    Citation: Journal of Biology 2007 6:9

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  13. Content type: Minireview

    A recent study revealing geographical and environmental barriers to gene flow in the harbour porpoise shows the great potential of 'landscape genetics' when applied to marine organisms.

    Authors: Michael Møller Hansen and Jakob Hemmer-Hansen

    Citation: Journal of Biology 2007 6:6

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  14. Content type: Research article

    Understanding gene function and genetic relationships is fundamental to our efforts to better understand biological systems. Previous studies systematically describing genetic interactions on a global scale ha...

    Authors: Alexandra B Byrne, Matthew T Weirauch, Victoria Wong, Martina Koeva, Scott J Dixon, Joshua M Stuart and Peter J Roy

    Citation: Journal of Biology 2007 6:8

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  15. Content type: Research article

    Cell growth underlies many key cellular and developmental processes, yet a limited number of studies have been carried out on cell-growth regulation. Comprehensive studies at the transcriptional, proteomic and...

    Authors: Juan I Castrillo, Leo A Zeef, David C Hoyle, Nianshu Zhang, Andrew Hayes, David CJ Gardner, Michael J Cornell, June Petty, Luke Hakes, Leanne Wardleworth, Bharat Rash, Marie Brown, Warwick B Dunn, David Broadhurst, Kerry O'Donoghue, Svenja S Hester…

    Citation: Journal of Biology 2007 6:4

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  16. Content type: Research article

    In animals with heteromorphic sex chromosomes, dosage compensation of sex-chromosome genes is thought to be critical for species survival. Diverse molecular mechanisms have evolved to effectively balance the e...

    Authors: Yuichiro Itoh, Esther Melamed, Xia Yang, Kathy Kampf, Susanna Wang, Nadir Yehya, Atila Van Nas, Kirstin Replogle, Mark R Band, David F Clayton, Eric E Schadt, Aldons J Lusis and Arthur P Arnold

    Citation: Journal of Biology 2007 6:2

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  17. Content type: Minireview

    Mechanisms to compensate for dosage differences of genes on sex chromosomes are widespread in animals and have been thought to be critical for viability. However, in birds, compensation is inefficient, implyin...

    Authors: Jennifer A Marshall Graves and Christine M Disteche

    Citation: Journal of Biology 2007 6:1

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  18. Content type: Research article

    Chemotherapy in cancer patients can be associated with serious short- and long-term adverse neurological effects, such as leukoencephalopathy and cognitive impairment, even when therapy is delivered systemical...

    Authors: Joerg Dietrich, Ruolan Han, Yin Yang, Margot Mayer-Pröschel and Mark Noble

    Citation: Journal of Biology 2006 5:22

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  19. Content type: Research article

    Secondary-ion mass spectrometry (SIMS) is an important tool for investigating isotopic composition in the chemical and materials sciences, but its use in biology has been limited by technical considerations. M...

    Authors: Claude Lechene, Francois Hillion, Greg McMahon, Douglas Benson, Alan M Kleinfeld, J Patrick Kampf, Daniel Distel, Yvette Luyten, Joseph Bonventre, Dirk Hentschel, Kwon Moo Park, Susumu Ito, Martin Schwartz, Gilles Benichou and Georges Slodzian

    Citation: Journal of Biology 2006 5:20

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  20. Content type: Minireview

    Biological materials are morphologically and chemically complex. A quantitative imaging tool is now available that can produce chemical, and even metabolic, information from morphological features as small as ...

    Authors: Peter Williams

    Citation: Journal of Biology 2006 5:18

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  21. Content type: Minireview

    One of the least understood aspects of animal development – the determination of body size – is currently the subject of intense scrutiny. A new study employs a modeling approach to expose the factors that mat...

    Authors: Joseph Parker and Laura A Johnston

    Citation: Journal of Biology 2006 5:15

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  22. Content type: Minireview

    The Ras/Raf/MEK/ERK signaling pathway is one of the best understood signal routes in cells. Recent studies add complexity to this cascade by indicating that the two ERK kinases, ERK1 (p44ERK1) and ERK2 (p42ERK2),...

    Authors: Alison C Lloyd

    Citation: Journal of Biology 2006 5:13

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  23. Content type: Comment

    The closely related mitogen-activated protein kinases ERK1 and ERK2 have now been shown to have opposing roles in Ras-mediated cell proliferation. I propose that dimerization of these highly related protein ki...

    Authors: Steven Pelech

    Citation: Journal of Biology 2006 5:12

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  24. Content type: Research article

    The mitogen-activated protein (MAP) kinases p44ERK1 and p42ERK2 are crucial components of the regulatory machinery underlying normal and malignant cell proliferation. A currently accepted model maintains that ERK...

    Authors: Chiara Vantaggiato, Ivan Formentini, Attilio Bondanza, Chiara Bonini, Luigi Naldini and Riccardo Brambilla

    Citation: Journal of Biology 2006 5:14

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  25. Content type: Research article

    The study of complex biological networks and prediction of gene function has been enabled by high-throughput (HTP) methods for detection of genetic and protein interactions. Sparse coverage in HTP datasets may...

    Authors: Teresa Reguly, Ashton Breitkreutz, Lorrie Boucher, Bobby-Joe Breitkreutz, Gary C Hon, Chad L Myers, Ainslie Parsons, Helena Friesen, Rose Oughtred, Amy Tong, Chris Stark, Yuen Ho, David Botstein, Brenda Andrews, Charles Boone, Olga G Troyanskya…

    Citation: Journal of Biology 2006 5:11

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  26. Content type: Minireview

    A systematic curation of the literature on Saccharomyces cerevisiae has yielded a comprehensive collection of experimentally observed interactions. This new resource augments current views of the topological stru...

    Authors: Joe Mellor and Charles DeLisi

    Citation: Journal of Biology 2006 5:10

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  27. Content type: Research article

    The nematode Caenorhabditis elegans has been used extensively to identify the genetic requirements for proper nervous system development and function. Key to this process is the direction of vesicles to the growi...

    Authors: Cheng-Wen Su, Suzanne Tharin, Yishi Jin, Bruce Wightman, Mona Spector, David Meili, Nancy Tsung, Christa Rhiner, Dimitris Bourikas, Esther Stoeckli, Gian Garriga, H Robert Horvitz and Michael O Hengartner

    Citation: Journal of Biology 2006 5:9

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  28. Content type: Minireview

    Simultaneous suppression of glial scarring and a general enhancement of axonal outgrowth has now been accomplished in an adult rat model of spinal cord transection. Transplantation of a novel astrocyte cell ty...

    Authors: Robert H Miller

    Citation: Journal of Biology 2006 5:6

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  29. Content type: Research article

    Transplantation of embryonic stem or neural progenitor cells is an attractive strategy for repair of the injured central nervous system. Transplantation of these cells alone to acute spinal cord injuries has n...

    Authors: Jeannette E Davies, Carol Huang, Christoph Proschel, Mark Noble, Margot Mayer-Proschel and Stephen JA Davies

    Citation: Journal of Biology 2006 5:7

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  30. Content type: Research article

    Dendritic cells (DCs) are central to the initiation and regulation of the adaptive immune response during infection. Modulation of DC function may therefore allow evasion of the immune system by pathogens. Sig...

    Authors: Owain R Millington, Caterina Di Lorenzo, R Stephen Phillips, Paul Garside and James M Brewer

    Citation: Journal of Biology 2006 5:5

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  31. Content type: Minireview

    The capacity of malarial infection to suppress the patient's immune responses both to the parasite and to other antigens has long puzzled researchers. A prime suspect, the parasite-produced pigment hemozoin, h...

    Authors: Britta C Urban and Stephen Todryk

    Citation: Journal of Biology 2006 5:4

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  32. Content type: Minireview

    Dosage compensation equalizes gene dosage between males and females, but its role in balancing expression between the X chromosome and the autosomes may be far more important. Now, DNA microarrays have shown e...

    Authors: Mimi K Cheng and Christine M Disteche

    Citation: Journal of Biology 2006 5:2

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